|
|
Myofascial pain syndrome in the pelvic area
Hujová, Kateřina ; Bitnar, Petr (advisor) ; Langerová, Marie (referee)
Myofascial pain syndrome (MFBS) in the pelvic region is characterized by the presence of trigger points (TrPs) in the pelvic floor (PF) muscles and pain that is localized directly in the pelvis but simultaneously radiates to surrounding structures. This pain is often difficult to distinguish from internal complaints, which are often mimiced or accompanied by the pain. This bachelor's thesis addresses the subject of pain in the pelvic region and TrPs, which are related to myofascial structures, particularly PD. In the theoretical part, it aims to bring together the existing knowledge on MFBS with a narrower focus on the pelvic region and to present a comprehensive examination procedure and treatment options. The examination of PD in MFBS should be comprehensive, including history, palpation, dynamic tests and pelvic region specific tests. Therapy is initiated with manual techniques (MT), includes therapeutic physical education (TPE) methods to integrate the pelvis into global movement patterns. Training awareness of PD and the ability to relax it play an important role as well. The psychological side of the person should not be neglected, as pelvic difficulties are related to the intimate parts, in many cases reducing the quality of life and limiting the performance of daily activities. For five...
|
|
|
Functional receptor alterations in urinary bladder and urethra in an animal model of chronic prostatitis-chronic pelvic pain syndrome
Rataj, Jan ; Štaud, František (advisor) ; Vokřál, Ivan (referee)
University of Gothenburg; Charles University Sahlgrenska Academy; Faculty of Pharmacy in Hradec Králové Institute of Neuroscience and Physiology; Department of Pharmacology & Toxicology Student: Jan Rataj Supervisor: Michael Winder, Ph.D.; Özgü Aydogdu, M.D.; Prof. PharmDr. František Štaud, Ph.D. Title of diploma thesis: Functional receptor alterations in urinary bladder and urethra in an animal model of chronic prostatitis-chronic pelvic pain syndrome Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common urological disorder. Current available pharmacological treatment options are not effective enough, mostly due to the etiology of CP/CPPS not being fully understood. My thesis aimed to examine potential urethral changes, using immunohistochemistry methods and an organ bath setup, in a rat model of CP/CPPS. The thesis also examined changes in the expression of muscarinic receptor subtype 3 (M3), β3 adrenoceptors, and purinergic P2X1 and P2X3 receptors in the urinary bladder using immunohistochemistry. Specifically, it was examined how these differ when celecoxib, BAY 60-2770 and a combination of celecoxib and BAY 60-2770 had been administered during the development of prostate inflammation in the rat model of CP/CPPS. The data show an upregulation of M3 receptors in animals with...
|
guest ::
